Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18614123 | 1.00 | TSHR (0.54) | TSHRKCNA5MAOBMAOALMNA | |
| SCHEMBL19243511 | 0.96 | TSHR (0.50) | TSHRKCNA5MAOBMAOALMNA | |
| SCHEMBL14094433 | 0.91 | MMP3 (0.46) | TSHRKCNA5PTPN5MMP2MMP3 | |
| SCHEMBL10619457 | 0.91 | MMP3 (0.46) | TSHRKCNA5PTPN5MMP2MMP3 | |
| SCHEMBL30525949 | 0.89 | KDM4E (0.50) | TSHRKCNA5MAOBLMNAMMP2 | |
| SCHEMBL29732960 | 0.87 | TSHR (0.54) | TSHRKCNA5MAOBMAOALMNA | |
| SCHEMBL20967371 | 0.86 | ABCG2 (0.50) | KCNA5PTPN5KMT2AMEN1F2 | |
| SCHEMBL20593959 | 0.86 | KCNA5 (0.50) | TSHRKCNA5MAOBMAOALMNA | |
| SCHEMBL22639761 | 0.85 | ESR1 (0.55) | TSHRKCNA5MAOBMAOAPTPN5 | |
| SCHEMBL19243514 | 0.85 | PTPN5 (0.56) | TSHRKCNA5PTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109384920-B | Phosphorus atom functionalized covalent triazine framework organic polymer and preparation and application thereof | 中国科学院兰州化学物理研究所 | 2021-02-02 | — | — | CN | disclosed |
| CN-109517187-B | Preparation method of covalent triazine framework polymer under open system | 中国科学院兰州化学物理研究所 | 2020-12-01 | — | — | CN | disclosed |