Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 12/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GYS1 | P13807 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2576552 | 0.83 | P2RX7 (0.46) | ACEP2RX7KMT2AMEN1POLB | |
| SCHEMBL2576550 | 0.83 | P2RX7 (0.46) | ACEP2RX7KMT2AMEN1POLB | |
| SCHEMBL1914212 | 0.77 | P2RX7 (0.51) | ACEP2RX7KMT2A | |
| SCHEMBL1651090 | 0.77 | P2RX7 (0.51) | ACEP2RX7KMT2A | |
| SCHEMBL1587390 | 0.77 | P2RX7 (0.51) | ACEP2RX7KMT2A | |
| SCHEMBL6694973 | 0.77 | ACE (0.44) | ACEP2RX7KMT2AMEN1POLB | |
| SCHEMBL15018763 | 0.76 | ACE (0.41) | ACEP2RX7KMT2AMEN1POLB | |
| SCHEMBL8859113 | 0.76 | ACE (0.41) | ACEP2RX7KMT2AMEN1POLB | |
| SCHEMBL19975095 | 0.75 | ACE (0.43) | ACEP2RX7KMT2AMEN1POLB | |
| SCHEMBL6705720 | 0.75 | ACE (0.43) | ACEP2RX7KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8735332-B2 | Use of pyroglutamic acid esters as gas hydrate inhibitors with improved biodegradability | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) | 2014-05-27 | — | — | US | disclosed |
| US-20100213408-A1 | Use of Pyroglutamic Acid Esters as Gas Hydrate Inhibitors With Improved Biodegradability | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) | 2010-08-26 | — | — | US | disclosed |