Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3975423 | 0.81 | KDM4E (0.69) | HDAC6KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3976218 | 0.80 | HDAC6 (0.62) | HDAC6KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8861233 | 0.80 | HDAC6 (0.62) | HDAC6KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL1161248 | 0.80 | HDAC6 (0.62) | HDAC6KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6837735 | 0.77 | KDM4E (0.69) | HDAC6KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL28490940 | 0.77 | HDAC6 (0.63) | HDAC6KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL11331858 | 0.76 | HDAC6 (0.58) | HDAC6KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL28506236 | 0.75 | HDAC6 (0.64) | HDAC6KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL28669206 | 0.75 | HDAC6 (0.60) | HDAC6KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL13381831 | 0.75 | HDAC6 (0.68) | HDAC6KDM4EALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111892545-B | Green synthesis method of 1-methyl-3-alkyl quinoxalinone compound | 怀化学院 | 2021-11-05 | — | — | CN | claimed |
| CN-111892545-A | Green synthesis method of 1-methyl-3-alkyl quinoxalinone compound | 怀化学院 | 2020-11-06 | — | — | CN | claimed |
| CN-111892545-B | Green synthesis method of 1-methyl-3-alkyl quinoxalinone compound | 怀化学院 | 2021-11-05 | — | — | CN | disclosed |
| CN-111892545-B | Green synthesis method of 1-methyl-3-alkyl quinoxalinone compound | 怀化学院 | 2021-11-05 | — | — | CN | disclosed |
| CN-111892545-B | Green synthesis method of 1-methyl-3-alkyl quinoxalinone compound | 怀化学院 | 2021-11-05 | — | — | CN | disclosed |
| CN-111892545-A | Green synthesis method of 1-methyl-3-alkyl quinoxalinone compound | 怀化学院 | 2020-11-06 | — | — | CN | disclosed |
| CN-111892545-A | Green synthesis method of 1-methyl-3-alkyl quinoxalinone compound | 怀化学院 | 2020-11-06 | — | — | CN | disclosed |
| CN-111892545-A | Green synthesis method of 1-methyl-3-alkyl quinoxalinone compound | 怀化学院 | 2020-11-06 | — | — | CN | disclosed |