Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 8/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30933408 | 1.00 | ALDH1A1 (0.49) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4501486 | 0.85 | ALDH1A1 (0.41) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL31510889 | 0.85 | ALDH1A1 (0.41) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL21622865 | 0.76 | ALDH1A1 (0.42) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL21623397 | 0.74 | ALK (0.48) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL24489537 | 0.73 | PTPN2 (0.42) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9219702 | 0.73 | KDM4E (0.49) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL23917084 | 0.72 | HPGD (0.39) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11823273 | 0.72 | ALDH1A1 (0.50) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL21622727 | 0.72 | ALDH1A1 (0.55) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1652554-B1 | Composition comprising at least one carboycanine, process of treating keratinic fibres, kit and use of said composition | OREAL (FR) | 2010-01-13 | — | — | EP | claimed |
| US-7425221-B2 | Composition comprising at least one substituted derivative of carbocyanine, method for treating keratin fibers using it, device and use | L'OREAL S.A. (FR) | 2008-09-16 | — | — | US | claimed |
| US-20060195990-A1 | Composition comprising at least one substituted derivative of carbocyanine, method for treating keratin fibers using it, device and use | L'OREAL S.A. (FR) | 2006-09-07 | — | — | US | claimed |
| EP-1652554-A1 | Composition comprising at least one carboycanine, process of treating keratinic fibres, kit and use of said composition | L'OREAL (FR) | 2006-05-03 | — | — | EP | claimed |
| WO-2006030127-A1 | COMPOSITION COMPRISING AT LEAST ONE SUBSTITUTED CARBOCYANINE DERIVATIVE, KERATIN FIBRE TREATMENT METHOD USING SAME, ASSOCIATED DEVICE AND USE THEREOF | L'OREAL (FR) | 2006-03-23 | — | — | WO | claimed |
| EP-1652554-B1 | Composition comprising at least one carboycanine, process of treating keratinic fibres, kit and use of said composition | OREAL (FR) | 2010-01-13 | — | — | EP | disclosed |
| US-7425221-B2 | Composition comprising at least one substituted derivative of carbocyanine, method for treating keratin fibers using it, device and use | L'OREAL S.A. (FR) | 2008-09-16 | — | — | US | disclosed |
| US-20060195990-A1 | Composition comprising at least one substituted derivative of carbocyanine, method for treating keratin fibers using it, device and use | L'OREAL S.A. (FR) | 2006-09-07 | — | — | US | disclosed |
| WO-2006030127-A1 | COMPOSITION COMPRISING AT LEAST ONE SUBSTITUTED CARBOCYANINE DERIVATIVE, KERATIN FIBRE TREATMENT METHOD USING SAME, ASSOCIATED DEVICE AND USE THEREOF | L'OREAL (FR) | 2006-03-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060195990-A1 | Composition comprising at least one substituted derivative of carbocyanine, method for treating keratin fibers using it, device and use | KRT18, KLK5, IK | ALDH1A1 825/4885MAPT 317/4885CYP1A2 1622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.