Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TLR2 | O60603 | 3/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27093787 | 0.91 | TLR2 (0.49) | KMT2ATLR2PTPN1MDM2 | |
| SCHEMBL27093790 | 0.91 | TLR2 (0.49) | KMT2ATLR2PTPN1MDM2 | |
| SCHEMBL18452250 | 0.91 | PTPN1 (0.45) | KMT2ATLR2PTPN1 | |
| SCHEMBL18477094 | 0.91 | PTPN1 (0.45) | KMT2ATLR2PTPN1 | |
| SCHEMBL22347004 | 0.88 | MDM4 (0.52) | KMT2ATLR2MDM2 | |
| SCHEMBL22347005 | 0.88 | MDM4 (0.52) | KMT2ATLR2MDM2 | |
| SCHEMBL29938558 | 0.88 | MDM4 (0.52) | KMT2ATLR2MDM2 | |
| SCHEMBL30919299 | 0.87 | PTPN1 (0.52) | KMT2ATLR2PTPN1 | |
| SCHEMBL25356641 | 0.87 | KMT2A (0.55) | KMT2ATLR2MDM2 | |
| SCHEMBL13401519 | 0.87 | KMT2A (0.55) | KMT2ATLR2MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112920092-A | Prodrugs of glutamine analogs | 约翰霍普金斯大学 | 2021-06-08 | — | — | CN | disclosed |
| CN-108290827-B | Prodrugs of glutamine analogs | 约翰霍普金斯大学 | 2021-01-01 | — | — | CN | disclosed |