Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 2/20 | 0.49 |
| ▸ | MDM4 | O15151 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.47 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27093787 | 1.00 | TLR2 (0.49) | TLR2MDM4TP53PTPN1CASP3 | |
| SCHEMBL22347005 | 0.96 | MDM4 (0.52) | TLR2MDM4TP53CASP3MDM2 | |
| SCHEMBL29938558 | 0.96 | MDM4 (0.52) | TLR2MDM4TP53CASP3MDM2 | |
| SCHEMBL22347004 | 0.96 | MDM4 (0.52) | TLR2MDM4TP53CASP3MDM2 | |
| SCHEMBL27093858 | 0.93 | PTPN1 (0.52) | TLR2MDM4TP53PTPN1CASP3 | |
| SCHEMBL27093852 | 0.93 | PTPN1 (0.52) | TLR2MDM4TP53PTPN1CASP3 | |
| SCHEMBL28500260 | 0.91 | KMT2A (0.47) | TLR2PTPN1MDM2KMT2A | |
| SCHEMBL30919299 | 0.91 | PTPN1 (0.52) | TLR2MDM4TP53PTPN1KMT2A | |
| SCHEMBL30919289 | 0.90 | PTPN1 (0.45) | TLR2PTPN1CASP3 | |
| SCHEMBL30919311 | 0.89 | PTPN1 (0.46) | TLR2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024097320-A1 | AZOTOMYCIN PRODRUGS WITH PREFERENTIAL TUMOR DELIVERY | THE JOHNS HOPKINS UNIVERSITY (US) | 2024-05-10 | — | — | WO | disclosed |
| EP-4322961-A1 | DENDRIMER-GLUTAMINE ANTAGONIST CONJUGATES AND METHODS OF USE THEREOF | The Johns Hopkins University (US) | 2024-02-21 | — | — | EP | disclosed |