Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9710697 | 0.79 | BRD4 (0.38) | KDM4EALDH1A1POLBKMT2AL3MBTL1 | |
| SCHEMBL2551281 | 0.77 | MAPT (0.49) | P2RX7MAPTCYP1A2CYP3A4KDM4E | |
| SCHEMBL8812476 | 0.76 | SMN1; SMN2 (0.35) | CYP1A2ALDH1A1POLBKMT2AL3MBTL1 | |
| SCHEMBL7489316 | 0.76 | RXFP1 (0.42) | MAPTKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL15199632 | 0.76 | MEN1 (0.41) | CYP1A2CYP3A4KDM4EALDH1A1KMT2A | |
| SCHEMBL16519359 | 0.73 | CYP1A2 (0.53) | MAPTCYP1A2KDM4EALDH1A1GAA | |
| SCHEMBL21232986 | 0.71 | MAPT (0.31) | MAPT | |
| SCHEMBL20713614 | 0.68 | — | — | |
| SCHEMBL22518496 | 0.68 | P2RX7 (0.46) | P2RX7MAPTCYP1A2CYP3A4KDM4E | |
| SCHEMBL12911102 | 0.68 | P2RX7 (0.42) | P2RX7MAPTCYP1A2CYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110105275-B | Amide derivatives, preparation method and medical application thereof | 上海海雁医药科技有限公司 | 2020-12-29 | — | — | CN | disclosed |