SCHEMBL28501337

SCHEMBL28501337

Cc1cccc(S(=O)(=O)O[C@H](C)COc2ccccc2Cc2ccccc2)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.39
HRH1 P35367 5/20 0.39
DRD2 P14416 2/20 0.39
DRD1 P21728 2/20 0.39
DRD4 P21917 1/20 0.39
DRD5 P21918 1/20 0.39
TP53 P04637 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
TSHR P16473 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
HPGD P15428 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
LMNA P02545 1/20 0.38
DRD3 P35462 1/20 0.38
SLC1A5 Q15758 1/20 0.37
HTR1A P08908 1/20 0.37
ADRA1D P25100 1/20 0.37
ADRA1A P35348 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17664993 0.87 HRH1 (0.41) ALDH1A1HRH1DRD2DRD1DRD4
SCHEMBL22974801 0.87 HRH1 (0.41) ALDH1A1HRH1DRD2DRD1DRD4
SCHEMBL17660558 0.87 HRH1 (0.41) ALDH1A1HRH1DRD2DRD1DRD4
SCHEMBL25259239 0.80 HRH1 (0.47) HRH1DRD2DRD1DRD4DRD5
SCHEMBL25218614 0.80 HRH1 (0.47) HRH1DRD2DRD1DRD4DRD5
SCHEMBL25216672 0.80 HRH1 (0.47) HRH1DRD2DRD1DRD4DRD5
SCHEMBL14778493 0.73 KMT2A (0.47) ALDH1A1SMN1; SMN2LMNAF2HTR6
SCHEMBL17646489 0.73 CA12 (0.39) ALDH1A1CYP1A2CYP3A4L3MBTL1SMN1; SMN2
SCHEMBL17646488 0.73 CA12 (0.39) ALDH1A1CYP1A2CYP3A4L3MBTL1SMN1; SMN2
SCHEMBL17646490 0.73 CA12 (0.39) ALDH1A1CYP1A2CYP3A4L3MBTL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112166106-B Cancer metastasis inhibitors by inhibiting cancer cell migration and invasion VS药物技术公司 2024-05-24 CN disclosed
CN-112166106-A Cancer metastasis inhibitors by inhibiting cancer cell migration and invasion 韩国生命工学硏究院 2021-01-01 CN disclosed