Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 5/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD1 | P21728 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD5 | P21918 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22974801 | 1.00 | HRH1 (0.41) | HRH1DRD2DRD1DRD4DRD5 | |
| SCHEMBL17660558 | 1.00 | HRH1 (0.41) | HRH1DRD2DRD1DRD4DRD5 | |
| SCHEMBL28501337 | 0.87 | ALDH1A1 (0.39) | HRH1DRD2DRD1DRD4DRD5 | |
| SCHEMBL27446340 | 0.85 | KDM4E (0.43) | ALDH1A1CYP1A2TSHRSMN1; SMN2LMNA | |
| SCHEMBL25259239 | 0.82 | HRH1 (0.47) | HRH1DRD2DRD1DRD4DRD5 | |
| SCHEMBL25218614 | 0.82 | HRH1 (0.47) | HRH1DRD2DRD1DRD4DRD5 | |
| SCHEMBL25216672 | 0.82 | HRH1 (0.47) | HRH1DRD2DRD1DRD4DRD5 | |
| SCHEMBL17646488 | 0.80 | CA12 (0.39) | ALDH1A1CYP1A2CYP3A4L3MBTL1SMN1; SMN2 | |
| SCHEMBL17646490 | 0.80 | CA12 (0.39) | ALDH1A1CYP1A2CYP3A4L3MBTL1SMN1; SMN2 | |
| SCHEMBL17646489 | 0.80 | CA12 (0.39) | ALDH1A1CYP1A2CYP3A4L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160095845-A1 | COMPOSITION COMPRISING (S)-(-)-BENPROPERINE FOR PREVENTING OR TREATING CANCER | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2016-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160095845-A1 | COMPOSITION COMPRISING (S)-(-)-BENPROPERINE FOR PREVENTING OR TREATING CANCER | BRCA1, MME, COMT | HRH1 1674/4885DRD2 543/4885DRD1 2129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.