Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | GLP1R | P43220 | 8/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TYMS | P04818 | 1/20 | 0.37 |
| ▸ | GART | P22102 | 1/20 | 0.37 |
| ▸ | ATIC | P31939 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28501358 | 0.88 | PTGS1 (0.45) | PTGS1PTGS2AKT1GLP1RBCHE | |
| SCHEMBL15096521 | 0.83 | PTGS1 (0.47) | PTGS1PTGS2GLP1RHPGDHTT | |
| SCHEMBL15096516 | 0.82 | POLB (0.45) | AKT1MEN1POLBKMT2ANPSR1 | |
| SCHEMBL31721990 | 0.81 | AKT1 (0.51) | PTGS1PTGS2AKT1GLP1RHDAC3 | |
| SCHEMBL29551996 | 0.81 | KMT2A (0.44) | GLP1RPOLBKMT2A | |
| SCHEMBL17732161 | 0.80 | PTGS1 (0.73) | PTGS1PTGS2HPGDHTTSMN1; SMN2 | |
| SCHEMBL22308463 | 0.80 | AKT1 (0.59) | AKT1BCHEACHEHTTMEN1 | |
| SCHEMBL22223503 | 0.80 | GLP1R (0.52) | PTGS1PTGS2GLP1RHPGDHTT | |
| SCHEMBL22223484 | 0.80 | PTGS1 (0.40) | PTGS1PTGS2AKT1HPGDHTT | |
| SCHEMBL22223483 | 0.80 | PTGS1 (0.51) | PTGS1PTGS2GLP1RTYMSGART |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112142855-A | Protein for diabetes treatment, protein conjugate and application thereof | 爱德迪安（北京）生物技术有限公司 | 2020-12-29 | — | — | CN | disclosed |