Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Ether. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ether SCHEMBL1665607 | 1.00 | GPR84 (0.53) | GPR84FFAR1FFAR4PLA2G2CUSP2 | |
| Ether SCHEMBL3229507 | 0.98 | GPR84 (0.51) | GPR84FFAR1FFAR4PLA2G2CUSP2 | |
| Acetic Acid SCHEMBL27916966 | 0.91 | GPR84 (0.62) | GPR84FFAR1FFAR4PLA2G2CKDM4E | |
| Acetic Acid SCHEMBL27916972 | 0.91 | GPR84 (0.62) | GPR84FFAR1FFAR4PLA2G2CKDM4E | |
| Acetic Acid SCHEMBL27899416 | 0.91 | GPR84 (0.62) | GPR84FFAR1FFAR4PLA2G2CKDM4E | |
| Acetic Acid SCHEMBL27899782 | 0.91 | GPR84 (0.62) | GPR84FFAR1FFAR4PLA2G2CKDM4E | |
| Acetic Acid SCHEMBL11506588 | 0.91 | GPR84 (0.62) | GPR84FFAR1FFAR4PLA2G2CKDM4E | |
| Acetic Acid SCHEMBL22288729 | 0.89 | GPR84 (0.60) | GPR84FFAR1FFAR4PLA2G2CKDM4E | |
| Bicarbonate SCHEMBL1081559 | 0.85 | GPR84 (0.64) | GPR84FFAR1FFAR4KDM4EDUSP3 | |
| Bicarbonate SCHEMBL8652008 | 0.85 | GPR84 (0.64) | GPR84FFAR1FFAR4KDM4EDUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112147842-A | Black photosensitive resin composition, black pattern and liquid crystal display device | 奇美实业股份有限公司 | 2020-12-29 | — | — | CN | disclosed |