Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 14/20 | 0.67 |
| ▸ | JAK3 | P52333 | 6/20 | 0.54 |
| ▸ | JAK1 | P23458 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18609413 | 0.86 | BTK (0.72) | BTK | |
| SCHEMBL17699765 | 0.85 | BTK (0.80) | BTK | |
| SCHEMBL28492348 | 0.84 | BTK (0.75) | BTKJAK3 | |
| SCHEMBL28055982 | 0.81 | BTK (0.84) | BTK | |
| SCHEMBL29782340 | 0.80 | BTK (1.00) | BTKJAK3 | |
| SCHEMBL17699589 | 0.80 | BTK (1.00) | BTKJAK3 | |
| SCHEMBL28494360 | 0.77 | BTK (0.81) | BTKJAK3 | |
| SCHEMBL28372661 | 0.75 | BTK (0.71) | BTK | |
| SCHEMBL16337822 | 0.74 | BTK (1.00) | BTK | |
| SCHEMBL17699806 | 0.73 | BTK (1.00) | BTKJAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110511209-B | Indole carboxamide compounds useful as kinase inhibitors | 百时美施贵宝公司 | 2022-07-05 | — | — | CN | disclosed |
| CN-107108583-B | Indole carboxamide compounds useful as kinase inhibitors | 百时美施贵宝公司 | 2020-11-13 | — | — | CN | disclosed |