Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP6 | P51161 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28497293 | 0.73 | ALDH1A1 (0.30) | — | |
| SCHEMBL28510247 | 0.72 | ALDH1A1 (0.36) | FABP6 | |
| SCHEMBL28508799 | 0.69 | PIK3CA (0.49) | — | |
| SCHEMBL28538572 | 0.66 | — | — | |
| SCHEMBL23832869 | 0.65 | FABP6 (0.41) | FABP6 | |
| SCHEMBL13035941 | 0.65 | FABP6 (0.41) | FABP6 | |
| SCHEMBL18614425 | 0.63 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL15996958 | 0.62 | FABP6 (0.41) | FABP6 | |
| SCHEMBL16858400 | 0.62 | ALDH1A1 (0.46) | FABP6 | |
| SCHEMBL31076265 | 0.62 | MAPT (0.35) | FABP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112409378-A | Tricyclic PI3K inhibitor compounds and methods of use thereof | 豪夫迈·罗氏有限公司 | 2021-02-26 | — | — | CN | disclosed |
| CN-108349996-B | Tricyclic PI3K inhibitor compounds and methods of use thereof | 豪夫迈·罗氏有限公司 | 2021-01-08 | — | — | CN | disclosed |