SCHEMBL28501987

SCHEMBL28501987

Nc1ccc(-c2ccc(C=CC(=O)O)cc2)c(N)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.54
CA12 O43570 3/20 0.49
CA1 P00915 3/20 0.49
CA2 P00918 3/20 0.49
CA3 P07451 3/20 0.49
CA4 P22748 3/20 0.49
CA6 P23280 3/20 0.49
CA5A P35218 3/20 0.49
CA7 P43166 3/20 0.49
CA9 Q16790 3/20 0.49
CA14 Q9ULX7 3/20 0.49
CA5B Q9Y2D0 3/20 0.49
HCAR2 Q8TDS4 2/20 0.49
AKR1B10 O60218 2/20 0.49
AKR1B1 P15121 2/20 0.49
DPP4 P27487 2/20 0.49
PKM P14618 2/20 0.49
ESR1 P03372 2/20 0.49
TYR P14679 1/20 0.49
ESR2 Q92731 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28181230 0.89 NPSR1 (0.53) NPSR1CA12CA1CA2CA3
SCHEMBL143559 0.80 CA12 (0.65) NPSR1CA12CA1CA2CA3
SCHEMBL1001682 0.80 CA12 (0.65) NPSR1CA12CA1CA2CA3
SCHEMBL143558 0.80 CA12 (0.65) NPSR1CA12CA1CA2CA3
SCHEMBL7260958 0.80 NPSR1 (0.67) NPSR1CA12CA1CA2CA3
SCHEMBL8973589 0.80 HDAC2 (0.60) NPSR1CA12CA1CA2CA3
Hydrochloric Acid SCHEMBL1403030 0.79 CA12 (0.63) NPSR1CA12CA1CA2CA3
Benzene SCHEMBL6912055 0.79 HCAR2 (0.68) NPSR1CA12CA1CA2CA3
Hydrochloric Acid SCHEMBL1403028 0.79 CA12 (0.63) NPSR1CA12CA1CA2CA3
Methyl Alcohol SCHEMBL29035811 0.77 KDM4E (0.63) NPSR1CA12CA1CA2CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112135890-A Liquid crystal aligning agent composition, method for preparing liquid crystal alignment film, and liquid crystal alignment film and liquid crystal display using same 株式会社LG化学 2020-12-25 CN disclosed