SCHEMBL7260958

SCHEMBL7260958

Nc1cccc(-c2ccc(C=CC(=O)O)cc2N)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.67
RXRA P19793 1/20 0.49
NR4A2 P43354 1/20 0.49
PTPN11 Q06124 2/20 0.47
ALDH1A1 P00352 5/20 0.45
KDM4E B2RXH2 4/20 0.45
HSD17B10 Q99714 3/20 0.45
HDAC3 O15379 2/20 0.45
HDAC4 P56524 2/20 0.45
HDAC1 Q13547 2/20 0.45
HDAC7 Q8WUI4 2/20 0.45
HDAC2 Q92769 2/20 0.45
HDAC10 Q969S8 2/20 0.45
HDAC11 Q96DB2 2/20 0.45
HDAC8 Q9BY41 2/20 0.45
HDAC6 Q9UBN7 2/20 0.45
HDAC9 Q9UKV0 2/20 0.45
HDAC5 Q9UQL6 2/20 0.45
LMNA P02545 2/20 0.45
GAA P10253 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6797343 0.84 NPSR1 (0.81) NPSR1ALDH1A1KDM4EHSD17B10HDAC3
SCHEMBL6797338 0.84 NPSR1 (0.81) NPSR1ALDH1A1KDM4EHSD17B10HDAC3
SCHEMBL1000884 0.81 NPSR1 (1.00) NPSR1ALDH1A1KDM4EHSD17B10HDAC3
SCHEMBL30791063 0.81 NPSR1 (1.00) NPSR1ALDH1A1KDM4EHSD17B10HDAC3
SCHEMBL1000885 0.81 NPSR1 (1.00) NPSR1ALDH1A1KDM4EHSD17B10HDAC3
SCHEMBL1003575 0.81 NPSR1 (1.00) NPSR1ALDH1A1KDM4EHSD17B10HDAC3
SCHEMBL29777960 0.81 NPSR1 (1.00) NPSR1ALDH1A1KDM4EHSD17B10HDAC3
SCHEMBL28501987 0.80 NPSR1 (0.54) NPSR1PTPN11ALDH1A1KDM4EHSD17B10
SCHEMBL2908080 0.76 NPSR1 (0.59) NPSR1ALDH1A1KDM4EHSD17B10HDAC3
SCHEMBL2908083 0.76 NPSR1 (0.59) NPSR1ALDH1A1KDM4EHSD17B10HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6642393-B2 Such as 2,5-(dihydroxybenzenecarboxylic octane)-dibenzoate-3,3',4,4' -tetracarboxylic acid anhydride for producing polyimides or polyamic acides having low water absorption; for use in cosmetics, aeronautics, and electronics KANEKA CORPORATION (JP) 2003-11-04 US disclosed
US-20020055610-A1 Novel polyimide compositions and novel acid dianhydrides to be used therein KANEKA CORPORATION (JP) 2002-05-09 US disclosed
US-6350845-B1 POLYAMIDEIMIDE COPOLYMERS FOR NONABSORBENT HEAT RESISTANT COMPOSITIONS KANEKA CORPORATION (JP) 2002-02-26 US disclosed
US-6303742-B1 CHARACTERIZED BY A CINNAMOYL GROUP OR A DERIVED CINNAMOYL GROUP INCORPORATED THEREIN AND BY PHOTO-REACTIVITY AND HEAT-REACTIVITY WHICH ARE INHERENT IN THE CINNAMOYL GROUP. KANEKAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2001-10-16 US disclosed