⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2850212 | 0.88 | — | — | |
| SCHEMBL27199 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL3854217 | 0.82 | — | — | |
| SCHEMBL1209814 | 0.82 | — | — | |
| Calcium SCHEMBL29393231 | 0.82 | — | — | |
| SCHEMBL31506470 | 0.79 | — | — | |
| SCHEMBL15321675 | 0.78 | — | — | |
| Hydroxyamine SCHEMBL10529382 | 0.76 | — | — | |
| Pyrrole SCHEMBL1986041 | 0.69 | — | — | |
| Carbamic Acid SCHEMBL10377016 | 0.67 | ACHE (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1435954-B1 | A PROCESS FOR THE PREPARATION OF HIGHlLY PUREAMLODIPINE BENZENESULFONATE | LEK PHARMACEUTICALS (SI) | 2010-01-13 | — | — | EP | disclosed |
| US-7153970-B2 | High purity amlodipine benzenesulfonate and a process for its preparation | LEK PHARMACEUTICALS D.D. (SI) | 2006-12-26 | — | — | US | disclosed |
| US-20040176606-A1 | High purity amlodipine benzenesulfonate and a process for its preparation | FURLAN BORUT (SI) | 2004-09-09 | — | — | US | disclosed |
| EP-1435954-A1 | HIGH PURITY AMLODIPINE BENZENESULFONATE AND A PROCESS FOR ITS PREPARATION | Lek Pharmaceutical and Chemical Co. D.D. (SI) | 2004-07-14 | — | — | EP | disclosed |
| WO-2003004025-A1 | HIGH PURITY AMLODIPINE BENZENESULFONATE AND A PROCESS FOR ITS PREPARATION | LEK PHARMACEUTICAL AND CHEMICAL COMPANY D.D. (DE) | 2003-01-16 | — | — | WO | disclosed |