Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 19/20 | 0.78 |
| ▸ | AXL | P30530 | 1/20 | 0.78 |
| ▸ | JAK1 | P23458 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29380081 | 0.88 | JAK2 (1.00) | JAK2AXLJAK1 | |
| SCHEMBL14331950 | 0.88 | JAK2 (1.00) | JAK2AXLJAK1 | |
| SCHEMBL28492504 | 0.81 | JAK2 (0.57) | JAK2AXLJAK1 | |
| SCHEMBL14377373 | 0.81 | JAK2 (1.00) | JAK2AXLJAK1 | |
| SCHEMBL21799097 | 0.81 | JAK2 (1.00) | JAK2AXLJAK1 | |
| SCHEMBL14377761 | 0.81 | JAK2 (1.00) | JAK2AXLJAK1 | |
| SCHEMBL14331926 | 0.80 | JAK2 (1.00) | JAK2AXLJAK1 | |
| SCHEMBL29379278 | 0.80 | JAK2 (1.00) | JAK2AXLJAK1 | |
| SCHEMBL31089956 | 0.80 | JAK2 (0.58) | JAK2JAK1 | |
| SCHEMBL28908042 | 0.80 | JAK2 (0.60) | JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109867676-B | Pyrrolopyrimidine derivative compound, pharmaceutical composition and application thereof | 北京普祺医药科技有限公司 | 2020-10-30 | — | — | CN | disclosed |