Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CB | P42338 | 4/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | RAB27A | P51159 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | AURKA | O14965 | 6/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 3/20 | 0.38 |
| ▸ | KDR | P35968 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28491690 | 0.92 | PIK3CB (0.49) | PIK3CBPIK3CDPIK3CAPIK3CGCHRM2 | |
| SCHEMBL28504254 | 0.90 | PIK3CB (0.46) | PIK3CBPIK3CDPIK3CAPIK3CGCHRM2 | |
| SCHEMBL23965973 | 0.90 | PIK3CB (0.58) | PIK3CBPIK3CDPIK3CAPIK3CGCHRM2 | |
| SCHEMBL28508539 | 0.88 | PIK3CB (0.47) | PIK3CBPIK3CDPIK3CAPIK3CGCHRM2 | |
| SCHEMBL28504404 | 0.87 | PIK3CB (0.46) | PIK3CBPIK3CDPIK3CAPIK3CGCHRM2 | |
| SCHEMBL22183750 | 0.81 | PIK3CB (0.45) | PIK3CBPIK3CDPIK3CAPIK3CGCHRM2 | |
| SCHEMBL23965974 | 0.81 | PIK3CB (0.60) | PIK3CBPIK3CDPIK3CAPIK3CGCHRM2 | |
| SCHEMBL24211157 | 0.80 | PIK3CB (0.56) | PIK3CBPIK3CDPIK3CAPIK3CGCHRM2 | |
| SCHEMBL23966084 | 0.79 | PIK3CB (0.58) | PIK3CBPIK3CDPIK3CAPIK3CGCHRM2 | |
| SCHEMBL23966009 | 0.79 | MTOR (0.36) | PIK3CBPIK3CAMTORHDAC1AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109516961-B | Aminoquinazolinone and aminoisoquinolinone derivatives and uses thereof | 浙江大学 | 2021-01-01 | — | — | CN | disclosed |