Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | XIAP | P98170 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TYK2 | P29597 | 4/20 | 0.47 |
| ▸ | JAK1 | P23458 | 2/20 | 0.47 |
| ▸ | JAK2 | O60674 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28499579 | 0.86 | KCNQ2 (0.48) | KMT2AMEN1MAPTLMNATYK2 | |
| SCHEMBL16583378 | 0.85 | PTGS2 (0.47) | KMT2AMEN1MAPTLMNATYK2 | |
| SCHEMBL28508979 | 0.84 | KLK7 (0.47) | KMT2AMEN1MAPTLMNATYK2 | |
| SCHEMBL28508980 | 0.84 | KLK7 (0.47) | KMT2AMEN1MAPTLMNATYK2 | |
| SCHEMBL14992199 | 0.80 | MAPT (0.42) | KMT2AMEN1MAPTLMNATYK2 | |
| SCHEMBL18188918 | 0.80 | MAPT (0.42) | KMT2AMEN1MAPTLMNATYK2 | |
| SCHEMBL22757697 | 0.80 | TYK2 (0.50) | KMT2AMAPTLMNATYK2JAK1 | |
| SCHEMBL28506241 | 0.79 | KLK7 (0.48) | KMT2AMEN1MAPTLMNATYK2 | |
| SCHEMBL16584729 | 0.79 | KLK7 (0.48) | KMT2AMEN1MAPTLMNATYK2 | |
| SCHEMBL14992154 | 0.78 | ITGB1 (0.41) | KMT2AMEN1MAPTLMNATYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105924433-B | Substituted aminopyrimidine compounds and use method and application thereof | 广东东阳光药业有限公司 | 2020-12-22 | — | — | CN | disclosed |