Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | LTA4H | P09960 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4046461 | 0.93 | LMNA (0.85) | LMNALTA4HCYP2D6ADRB2ADRB1 | |
| SCHEMBL9713476 | 0.93 | LMNA (0.85) | LMNALTA4HCYP2D6ADRB2ADRB1 | |
| SCHEMBL1496544 | 0.93 | LMNA (0.85) | LMNALTA4HCYP2D6ADRB2ADRB1 | |
| SCHEMBL4050984 | 0.87 | LMNA (0.59) | LMNALTA4HADRB2ADRB1MEN1 | |
| SCHEMBL50453 | 0.86 | LMNA (1.00) | LMNACYP2D6ADRB2ADRB1ADRB3 | |
| SCHEMBL2943775 | 0.86 | LMNA (1.00) | LMNACYP2D6ADRB2ADRB1ADRB3 | |
| SCHEMBL3254859 | 0.86 | LMNA (1.00) | LMNACYP2D6ADRB2ADRB1ADRB3 | |
| SCHEMBL1618880 | 0.86 | LMNA (1.00) | LMNACYP2D6ADRB2ADRB1ADRB3 | |
| SCHEMBL14570065 | 0.84 | LMNA (0.67) | LMNACYP2D6PTGS1MAPTKDM4E | |
| SCHEMBL1496750 | 0.84 | LMNA (0.67) | LMNACYP2D6PTGS1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112174784-A | Crystal form A of 1- (4-phenoxyphenoxy) -2-propanol and preparation method and application thereof | 江苏龙灯化学有限公司 | 2021-01-05 | — | — | CN | disclosed |