Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21268737 | 0.93 | MAPT (0.39) | — | |
| SCHEMBL21281509 | 0.93 | MAPT (0.39) | — | |
| SCHEMBL21268734 | 0.93 | MAPT (0.39) | — | |
| SCHEMBL21274025 | 0.91 | KMT2A (0.41) | — | |
| SCHEMBL21274023 | 0.91 | KMT2A (0.41) | — | |
| SCHEMBL21273967 | 0.90 | TBK1 (0.33) | — | |
| SCHEMBL21274262 | 0.90 | MAPT (0.32) | — | |
| SCHEMBL21274379 | 0.90 | CHRNA10 (0.37) | — | |
| SCHEMBL21274264 | 0.90 | MAPT (0.32) | — | |
| SCHEMBL21274295 | 0.90 | CDK8 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112105357-A | Pharmaceutically acceptable 6,5 heterobicyclic derivatives | UCB生物制药有限责任公司 | 2020-12-18 | — | — | CN | claimed |
| CN-112105357-A | Pharmaceutically acceptable 6,5 heterobicyclic derivatives | UCB生物制药有限责任公司 | 2020-12-18 | — | — | CN | disclosed |