Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 15/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 11/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2850405 | 1.00 | ADRB2 (0.46) | ADRB2CHRM3ADRB1CHRM2 | |
| SCHEMBL10242316 | 0.91 | ADRB2 (0.53) | ADRB2CHRM3ADRB1 | |
| SCHEMBL10242799 | 0.90 | ADRB2 (0.47) | ADRB2CHRM3ADRB1CHRM2 | |
| SCHEMBL2143065 | 0.83 | CHRM3 (0.39) | ADRB2CHRM3CHRM2 | |
| SCHEMBL2141468 | 0.82 | CHRM3 (0.41) | ADRB2CHRM3ADRB1CHRM2 | |
| SCHEMBL2141452 | 0.82 | CHRM3 (0.41) | ADRB2CHRM3ADRB1CHRM2 | |
| SCHEMBL10242312 | 0.81 | ADRB2 (0.65) | ADRB2CHRM3ADRB1 | |
| SCHEMBL2141729 | 0.81 | CHRM3 (0.40) | ADRB2CHRM3CHRM2 | |
| SCHEMBL2141707 | 0.81 | CHRM3 (0.40) | ADRB2CHRM3CHRM2 | |
| SCHEMBL12101027 | 0.81 | ADRB2 (0.49) | ADRB2CHRM3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2242759-A1 | COMPOUNDS | AstraZeneca AB (SE) | 2010-10-27 | — | — | EP | disclosed |
| WO-2009098448-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2009-08-13 | — | — | WO | disclosed |