Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 9/20 | 0.55 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.42 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.34 |
| ▸ | LOX | P28300 | 1/20 | 0.34 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.34 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5888962 | 0.80 | CYP2A6 (0.40) | CYP2A6PTK2 | |
| SCHEMBL5110030 | 0.79 | AHR (0.48) | CYP2A6PTK2 | |
| SCHEMBL3666921 | 0.77 | CYP2A6 (0.53) | CYP2A6LOXL2PTK2 | |
| SCHEMBL9413208 | 0.75 | CSNK2A1 (0.46) | CSNK2A1 | |
| SCHEMBL4771 | 0.74 | CYP2A6 (0.47) | CYP2A6PTK2 | |
| SCHEMBL3669814 | 0.73 | CDK8 (0.48) | CYP2A6LOXL2 | |
| SCHEMBL30803440 | 0.72 | CSNK2A1 (1.00) | CSNK2A1CSNK2A2CSNK2BCSNK2A3CYP2A6 | |
| SCHEMBL28511962 | 0.72 | CSNK2A1 (0.44) | CSNK2A1CSNK2A2CSNK2BCSNK2A3NSD2 | |
| SCHEMBL21201466 | 0.72 | ADH5 (0.52) | — | |
| SCHEMBL21201361 | 0.70 | DHODH (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112243374-A | SREBP inhibitors comprising a 6-membered central ring | 卡普勒斯疗法有限责任公司 | 2021-01-19 | — | — | CN | disclosed |