Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.61 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 2/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23373231 | 0.89 | GPR119 (0.63) | GPR119CHEK2ALDH1A1PDE4APDE4B | |
| SCHEMBL3342716 | 0.89 | GPR119 (0.66) | GPR119CHEK2ALDH1A1PDE4APDE4B | |
| SCHEMBL22533161 | 0.88 | GPR119 (0.61) | GPR119CHEK2ALDH1A1PDE4APDE4B | |
| SCHEMBL3342725 | 0.88 | GPR119 (0.61) | GPR119CHEK2ALDH1A1PDE4APDE4B | |
| SCHEMBL3344947 | 0.88 | GPR119 (0.61) | GPR119CHEK2ALDH1A1PDE4APDE4B | |
| SCHEMBL1375821 | 0.86 | GPR119 (0.60) | GPR119CHEK2ALDH1A1PDE4APDE4B | |
| SCHEMBL1373456 | 0.86 | GPR119 (0.60) | GPR119CHEK2ALDH1A1PDE4APDE4B | |
| SCHEMBL1376141 | 0.86 | GPR119 (0.60) | GPR119CHEK2ALDH1A1PDE4APDE4B | |
| SCHEMBL19838571 | 0.86 | GPR119 (0.60) | GPR119CHEK2ALDH1A1PDE4APDE4B | |
| SCHEMBL8546356 | 0.86 | GPR119 (0.60) | GPR119CHEK2ALDH1A1PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112110936-B | Tetrahydroquinoline derivative and preparation method and application thereof | 沈阳药科大学 | 2021-12-07 | — | — | CN | disclosed |
| CN-112110936-A | Tetrahydroquinoline derivative and preparation method and application thereof | 沈阳药科大学 | 2020-12-22 | — | — | CN | disclosed |