SCHEMBL28504374

SCHEMBL28504374

OB(O)c1cc(F)c2ccccc2c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
HPRT1 P00492 1/20 0.42
ENPP2 Q13822 2/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39
CA5A P35218 1/20 0.39
CA7 P43166 1/20 0.39
CA14 Q9ULX7 1/20 0.39
CA5B Q9Y2D0 1/20 0.39
TRPM4 Q8TD43 1/20 0.38
HSD17B10 Q99714 3/20 0.37
ALDH1A1 P00352 2/20 0.37
HIF1A Q16665 1/20 0.37
CYP1B1 Q16678 1/20 0.37
NQO2 P16083 1/20 0.36
MGLL Q99685 4/20 0.35
KDM4E B2RXH2 2/20 0.35
MEN1 O00255 1/20 0.35
CYP1A2 P05177 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5778117 0.78 CA1 (0.53) CA1CA2ENPP2ALDH1A1MGLL
SCHEMBL29951741 0.78 CA1 (0.53) CA1CA2ENPP2ALDH1A1MGLL
SCHEMBL29954404 0.78 NQO2 (0.57) CA1CA2ENPP2CA4CA6
SCHEMBL23205873 0.76 CYP1A2 (0.55) CA1CA2ENPP2CA4CA6
SCHEMBL17395921 0.76 CA1 (0.50) CA1CA2ENPP2CA4CA6
SCHEMBL29955464 0.76 CYP1A2 (0.55) CA1CA2ENPP2CA4CA6
SCHEMBL29957092 0.76 CA1 (0.50) CA1CA2HPRT1ENPP2CA4
SCHEMBL29958113 0.76 CA1 (0.50) CA1CA2ENPP2CA4CA6
SCHEMBL29954594 0.76 CA1 (0.46) CA1CA2ENPP2CA4CA6
SCHEMBL29953386 0.74 CA1 (0.48) CA1CA2ENPP2CA4CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112110896-B Organic electroluminescent material and application thereof 北京鼎材科技有限公司 2024-02-09 CN disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
CN-112110896-A Organic electroluminescent material and application thereof 北京鼎材科技有限公司 2020-12-22 CN disclosed
CN-112117384-A Organic electroluminescent material and application thereof 北京鼎材科技有限公司 2020-12-22 CN disclosed