SCHEMBL29957092

SCHEMBL29957092

Nc1cc(B(O)O)cc2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
ALDH1A1 P00352 4/20 0.45
HSD17B10 Q99714 3/20 0.45
HPGD P15428 2/20 0.45
CYP3A4 P08684 1/20 0.45
TSHR P16473 1/20 0.45
KEAP1 Q14145 1/20 0.45
HPRT1 P00492 1/20 0.42
KDM4E B2RXH2 3/20 0.41
ENPP2 Q13822 2/20 0.41
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39
CA5A P35218 1/20 0.39
CA7 P43166 1/20 0.39
CA14 Q9ULX7 1/20 0.39
CA5B Q9Y2D0 1/20 0.39
POLB P06746 1/20 0.38
HTT P42858 1/20 0.38
RAD52 P43351 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29957738 0.78 CA1 (0.53) CA1CA2ALDH1A1HSD17B10HPGD
SCHEMBL29954404 0.78 NQO2 (0.57) CA1CA2ALDH1A1HSD17B10HPGD
SCHEMBL23205873 0.76 CYP1A2 (0.55) CA1CA2ALDH1A1HSD17B10HPGD
SCHEMBL29958113 0.76 CA1 (0.50) CA1CA2ALDH1A1HSD17B10HPGD
SCHEMBL29955464 0.76 CYP1A2 (0.55) CA1CA2ALDH1A1HSD17B10HPGD
SCHEMBL17395921 0.76 CA1 (0.50) CA1CA2ALDH1A1HSD17B10HPGD
SCHEMBL28504374 0.76 CA1 (0.50) CA1CA2ALDH1A1HSD17B10HPGD
SCHEMBL29953386 0.74 CA1 (0.48) CA1CA2ALDH1A1HSD17B10HPGD
SCHEMBL275940 0.73 CA1 (0.69) CA1CA2ALDH1A1HSD17B10HPGD
SCHEMBL29955961 0.73 CA1 (0.69) CA1CA2ALDH1A1HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed