SCHEMBL28504665

SCHEMBL28504665

Fc1c(Br)c(F)c(C(F)(F)F)c(F)c1C(F)(F)F

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30377798 0.94 TSHR (0.31) TSHRSMN1; SMN2
SCHEMBL30377727 0.88 TSHR (0.33) TSHRSMN1; SMN2
SCHEMBL2000228 0.88 TSHR (0.33) TSHRSMN1; SMN2
SCHEMBL1995717 0.88 SMN1; SMN2 (0.35) TSHRSMN1; SMN2
SCHEMBL5373278 0.85 SMN1; SMN2 (0.34) TSHRSMN1; SMN2
SCHEMBL30378537 0.85 SMN1; SMN2 (0.34) TSHRSMN1; SMN2
SCHEMBL30378024 0.85
SCHEMBL1998599 0.83 SMN1; SMN2 (0.37) TSHRSMN1; SMN2
SCHEMBL4128954 0.80 TSHR (0.32) TSHRSMN1; SMN2
SCHEMBL11712009 0.76 SMN1; SMN2 (0.31) TSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111960917-B Compound 1-bromo-2, 4, 6-trifluoro-3, 5-bistrifluoromethylbenzene and preparation method thereof 浙江永太科技股份有限公司 2022-06-17 CN claimed
CN-111960917-A Novel compound 1-bromo-2, 4, 6-trifluoro-3, 5-bistrifluoromethylbenzene and preparation method thereof 浙江永太科技股份有限公司 2020-11-20 CN claimed
CN-111960917-B Compound 1-bromo-2, 4, 6-trifluoro-3, 5-bistrifluoromethylbenzene and preparation method thereof 浙江永太科技股份有限公司 2022-06-17 CN disclosed
CN-111960917-B Compound 1-bromo-2, 4, 6-trifluoro-3, 5-bistrifluoromethylbenzene and preparation method thereof 浙江永太科技股份有限公司 2022-06-17 CN disclosed
CN-111960917-B Compound 1-bromo-2, 4, 6-trifluoro-3, 5-bistrifluoromethylbenzene and preparation method thereof 浙江永太科技股份有限公司 2022-06-17 CN disclosed
CN-111960917-A Novel compound 1-bromo-2, 4, 6-trifluoro-3, 5-bistrifluoromethylbenzene and preparation method thereof 浙江永太科技股份有限公司 2020-11-20 CN disclosed
CN-111960917-A Novel compound 1-bromo-2, 4, 6-trifluoro-3, 5-bistrifluoromethylbenzene and preparation method thereof 浙江永太科技股份有限公司 2020-11-20 CN disclosed