Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.54 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | CTSK | P43235 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL30636857 | 0.92 | KDM4E (0.54) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL28336639 | 0.85 | KMT2A (0.67) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL9448420 | 0.85 | NPC1 (0.59) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL5365142 | 0.84 | KDM4E (0.65) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL10911824 | 0.83 | ALDH1A1 (0.68) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL14202778 | 0.83 | KDM4E (0.56) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL14270915 | 0.83 | KDM4E (0.56) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL3358264 | 0.83 | ALDH1A1 (0.62) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL31128489 | 0.82 | KDM4E (0.51) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL5947666 | 0.81 | KDM4E (0.58) | KDM4EALDH1A1HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111801121-B | 2-PMPA prodrugs for healthy tissue protection during PSMA-targeted cancer imaging or radiation therapy | 约翰霍普金斯大学 | 2023-12-01 | — | — | CN | disclosed |
| CN-112638431-A | Positron Emission Tomography (PET) radiotracers for imaging macrophage colony stimulating factor 1 receptor (CSF1R) in neuroinflammation | 约翰霍普金斯大学 | 2021-04-09 | — | — | CN | disclosed |
| CN-111655258-A | Compositions for cryopreservation and methods of use thereof | 常青树生物科学公司 | 2020-09-11 | — | — | CN | disclosed |