Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28510293 | 0.79 | TSHR (0.38) | TSHR | |
| SCHEMBL27502516 | 0.78 | LMNA (0.33) | LMNAHSD17B10 | |
| SCHEMBL3075311 | 0.75 | HSD17B10 (0.34) | LMNAHSD17B10 | |
| SCHEMBL17956497 | 0.74 | LMNA (0.35) | TSHRLMNAHSD17B10 | |
| SCHEMBL16013251 | 0.74 | LMNA (0.31) | LMNAHSD17B10 | |
| SCHEMBL12168462 | 0.72 | LMNA (0.34) | LMNAHSD17B10 | |
| SCHEMBL28887202 | 0.71 | TSHR (0.37) | TSHR | |
| SCHEMBL23547936 | 0.70 | TSHR (0.34) | TSHR | |
| Urea SCHEMBL29104387 | 0.70 | TSHR (0.48) | TSHRLMNAHSD17B10 | |
| SCHEMBL13737752 | 0.70 | TSHR (0.48) | TSHRLMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112105385-A | IRAK degrading agents and uses thereof | 凯麦拉医疗公司 | 2020-12-18 | — | — | CN | disclosed |