SCHEMBL28505

SCHEMBL28505

CCCC[Sn](CCCC)(CCCC)c1ccccn1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP19A1 P11511 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
KDM4E B2RXH2 2/20 0.38
LMNA P02545 2/20 0.38
HTT P42858 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
ALOX12 P18054 2/20 0.38
USP2 O75604 1/20 0.38
ALOX15 P16050 1/20 0.38
NPC1 O15118 1/20 0.38
HSP90AA1 P07900 1/20 0.38
RAB9A P51151 1/20 0.38
KCNA5 P22460 1/20 0.36
KCNH2 Q12809 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4037008 1.00 CYP1A2 (0.41) CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19
SCHEMBL29390052 1.00 CYP1A2 (0.41) CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19
SCHEMBL30275457 0.98 CYP1A2 (0.40) CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19
SCHEMBL31024051 0.98 CYP1A2 (0.40) CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19
SCHEMBL14689460 0.96 LMNA (0.40) CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19
SCHEMBL19307688 0.96 LMNA (0.40) CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19
Methylamine SCHEMBL26629017 0.96 CYP1A2 (0.39) CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19
SCHEMBL15529304 0.93 KDM4E (0.43) CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19
SCHEMBL2116198 0.88 KCNA5 (0.38) CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19
Iodide SCHEMBL28032261 0.83 CYP1A2 (0.40) CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3748 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114957341-B Spiropyran platinum complex, preparation thereof and application thereof in light-operated hand-light switch material 杭州师范大学 2024-06-25 CN claimed
CN-117430642-A Binuclear platinum complex with adjustable luminous color and preparation and application thereof 杭州师范大学 2024-01-23 CN claimed
CN-114773393-B Compound, preparation method thereof and circularly polarized luminescent material containing compound 中国科学院化学研究所 2023-10-27 CN claimed
CN-116037211-A Cobalt-based complex catalyst and preparation method and application thereof 合肥工业大学 2023-05-02 CN claimed
CN-114957341-A Spiropyran platinum complex, preparation thereof and application thereof in light-operated chiral switch material 杭州师范大学 2022-08-30 CN claimed
CN-114773393-A Compound, preparation method thereof and circular polarization luminescent material containing compound 中国科学院化学研究所 2022-07-22 CN claimed
CN-113477241-B Ternary composite photocatalyst and preparation method and application thereof 华南理工大学 2021-12-17 CN claimed
CN-113477241-A Ternary composite photocatalyst and preparation method and application thereof 华南理工大学 2021-10-08 CN claimed
US-9708432-B2 Highly sensitive (meth)acrylate and radical curable material AUTONETWORKS TECHNOLOGIES, LTD. (JP) 2017-07-18 US claimed
US-9611337-B2 Chain transfer agent, photosensitive composition, cured product of photosensitive composition, and method for curing photosensitive composition AUTONETWORKS TECHNOLOGIES, LTD. (JP) 2017-04-04 US claimed
US-20260146035-A1 FUSED BICYCLIC COMPOUNDS AND THEIR USE AS MER AND AXL INHIBITORS DONG-A ST CO., LTD. (KR) 2026-05-28 US disclosed
US-12637426-B2 1-cyano-pyrrolidine compounds as USP30 inhibitors MISSION THERAPEUTICS LIMITED (GB) 2026-05-26 US disclosed
EP-4745117-A1 NOVEL INDENONE DERIVATIVE AND USE THEREOF Amyloid Solution Inc. (KR) 2026-05-20 EP disclosed
EP-4743455-A1 SARM1 INHIBITORS F. Hoffmann-La Roche AG (CH) 2026-05-20 EP disclosed
EP-4741392-A1 1H-PYRAZOLO[4,3-C]PYRIDINE COMPOUND, AND COMPOSITION THEREOF AND USE THEREOF Shenzhen TargetRx Co., Ltd. (CN) 2026-05-13 EP disclosed
WO-1993021178-A1 INDOLE DERIVATIVES AS 5-HT1-LIKE AGONISTS PFIZER LIMITED (GB) 1993-10-28 WO disclosed
WO-1993010820-A1 ENHANCED TRIPLE-HELIX AND DOUBLE-HELIX FORMATION WITH OLIGOMERS CONTAINING MODIFIED PYRIMIDINES GILEAD SCIENCES, INC. (US) 1993-06-10 WO disclosed
EP-0514942-A1 Novel benzopyran derivatives and processes for the preparation thereof KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1992-11-25 EP disclosed
EP-0506363-A1 6-Heterocyclic-4-amino-1,3,4,5-tetrahydrobenz[cd]indoles ELI LILLY AND COMPANY (US) 1992-09-30 EP disclosed
EP-0506369-A1 6-Heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz[CD]indoles ELI LILLY AND COMPANY (US) 1992-09-30 EP disclosed