Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | TP53 | P04637 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | CCR1 | P32246 | 3/20 | 0.57 |
| ▸ | CCR5 | P51681 | 3/20 | 0.57 |
| ▸ | CCR8 | P51685 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | ALPL | P05186 | 2/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.57 |
| ▸ | ALPI | P09923 | 1/20 | 0.57 |
| ▸ | ALPG | P10696 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | METAP1 | P53582 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20919383 | 0.80 | KDM4E (0.68) | KDM4ETP53SMN1; SMN2LMNACCR1 | |
| SCHEMBL30203797 | 0.79 | — | — | |
| SCHEMBL80955 | 0.79 | — | — | |
| SCHEMBL18211777 | 0.78 | KDM4E (0.50) | KDM4ETP53SMN1; SMN2LMNACCR1 | |
| Hydrochloric Acid SCHEMBL7237591 | 0.77 | NPC1 (0.50) | KDM4ETP53SMN1; SMN2CYP1A2NPC1 | |
| Water SCHEMBL28236237 | 0.77 | NPC1 (0.50) | KDM4ETP53SMN1; SMN2CYP1A2NPC1 | |
| SCHEMBL18891533 | 0.77 | ALDH1A1 (0.44) | KDM4ETP53SMN1; SMN2LMNATDP1 | |
| SCHEMBL10958587 | 0.77 | KDM4E (0.63) | KDM4ETP53SMN1; SMN2LMNACCR1 | |
| Hydrochloric Acid SCHEMBL7238498 | 0.76 | NPC1 (0.49) | KDM4ETP53SMN1; SMN2CYP1A2NPC1 | |
| Hydrochloric Acid SCHEMBL4902758 | 0.75 | SMN1; SMN2 (0.61) | KDM4ETP53SMN1; SMN2LMNACCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108383779-B | Preparation method of 3 '-aryl-2, 2' -bipyridine-6-formamide derivative | 华侨大学 | 2021-02-02 | — | — | CN | claimed |
| CN-110078661-B | Preparation method of 3-alkenyl-2, 2' -bipyridine-6-formamide derivative | 华侨大学 | 2022-07-29 | — | — | CN | disclosed |
| CN-110078661-B | Preparation method of 3-alkenyl-2, 2' -bipyridine-6-formamide derivative | 华侨大学 | 2022-07-29 | — | — | CN | disclosed |
| CN-110078662-B | Preparation method of 3-acyl methyl-2, 2' -bipyridine-6-formamide derivative | 华侨大学 | 2022-03-04 | — | — | CN | disclosed |
| CN-108383779-B | Preparation method of 3 '-aryl-2, 2' -bipyridine-6-formamide derivative | 华侨大学 | 2021-02-02 | — | — | CN | disclosed |
| CN-108383779-B | Preparation method of 3 '-aryl-2, 2' -bipyridine-6-formamide derivative | 华侨大学 | 2021-02-02 | — | — | CN | disclosed |