SCHEMBL28506

SCHEMBL28506

C=[C]C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21200706 0.95
SCHEMBL7533424 0.67
SCHEMBL459761 0.67
SCHEMBL7135436 0.62
SCHEMBL443045 0.59
SCHEMBL207875 0.59
SCHEMBL465091 0.56
SCHEMBL15416025 0.56
SCHEMBL16499852 0.56
SCHEMBL144415 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 760 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118324965-A Modified ETFE resin, preparation method thereof and application thereof in high-flame-retardance copolymerized ETFE coating 格林斯达(北京)环保科技股份有限公司 2024-07-12 CN claimed
US-11788138-B2 Nucleic acid sequencing using affinity reagents MGI TECH CO., LTD. (CN) 2023-10-17 US claimed
US-20230148194-A1 SUBSTITUTED AMINOQUINOLONES AS DGKALPHA INHIBITORS FOR IMMUNE ACTIVATION BAYER AKTIENGESELLSCHAFT (DE) 2023-05-11 US claimed
EP-4112741-A1 STEPWISE SEQUENCING BY NON-LABELED REVERSIBLE TERMINATORS OR NATURAL NUCLEOTIDES MGI Tech Co., Ltd. (CN) 2023-01-04 EP claimed
CN-115003665-A Substituted aminoquinolones as immunoactive DGK alpha inhibitors 拜耳公司 2022-09-02 CN claimed
CN-113024349-B 3, 3-difluoro-1, 5-hexadiene compound and preparation method and application thereof 南京工业大学 2022-06-07 CN claimed
EP-3565905-B1 NUCLEIC ACID SEQUENCING USING AFFINITY REAGENTS MGI TECH CO LTD (CN) 2022-05-25 EP claimed
CN-110528293-B Flame-retardant antifouling synthetic leather and preparation method thereof 武汉天鸣集团有限公司 2022-01-18 CN claimed
WO-2021105117-A1 SUBSTITUTED AMINOQUINOLONES AS DGKALPHA INHIBITORS FOR IMMUNE ACTIVATION BAYER AKTIENGESELLSCHAFT (DE) 2021-06-03 WO claimed
CN-112778308-A Fused tricyclic derivatives as FGFR4 inhibitors 齐鲁制药有限公司 2021-05-11 CN claimed
WO-2005014580-A1 PYRIDYL PIPERAZINYL UREAS JANSSEN PHARMACEUTICA, N.V. (BE) 2005-02-17 WO claimed
US-20030153505-A1 Dolastatin 15 derivatives BASF AKTIENGESELLSCHAFT (DE) 2003-08-14 US claimed
US-6458765-B1 POLYPEPTIDES AS ANTICANCER AGENTS AND AGAINST CELL PROLIFERATION BASF AKTIENGESELLSCHAFT (DE) 2002-10-01 US claimed
US-6143721-A FOR TREATING CANCER IN MAMMALS BASF AKTIENGESELLSCHAFT (DE) 2000-11-07 US claimed
CN-1264388-A Dolastatin 15 derivatives ABSF AG (DE) 2000-08-23 CN claimed
EP-0991658-A1 DOLASTATIN 15 DERIVATIVES BASF AKTIENGESELLSCHAFT (DE) 2000-04-12 EP claimed
WO-1999003879-A1 DOLASTATIN 15 DERIVATIVES BASF AKTIENGESELLSCHAFT (DE) 1999-01-28 WO claimed
CN-1023476-C PROCESS OF PREPARING TRIFLUOROMETHYLVINYL DERIVATIVES STARTING WITH APPROPRIATE HALOGENOVINYL DERIVATIVES ROUSSEL UCLAF (FR) 1994-01-12 CN claimed
US-4920231-A Reacting with trifluoroacetic acid with halovinyl compound in presence of cuprous salt ROUSSEL UCLAF (FR) 1990-04-24 US claimed
CN-1036561-A The novel method for preparing the trifluoromethyl ethenyl derivatives from suitable halogenated vinyl derivative ROUSSEL UCLAF (FR) 1989-10-25 CN claimed