Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8319149 | 0.84 | TSHR (0.37) | SMN1; SMN2NPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL2510973 | 0.83 | KMT2A (0.50) | F2LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL1249246 | 0.81 | HPGD (0.53) | F2LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL28495717 | 0.81 | HPGD (0.53) | F2LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL27045573 | 0.80 | F2 (0.47) | F2LMNATSHRKMT2AMEN1 | |
| SCHEMBL1266020 | 0.80 | F2 (0.47) | F2LMNATSHRKMT2AMEN1 | |
| SCHEMBL29098438 | 0.80 | HPGD (0.52) | F2LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL24120719 | 0.79 | SIGMAR1 (0.56) | F2LMNATSHRKMT2AMEN1 | |
| SCHEMBL226315 | 0.79 | KMT2A (0.55) | LMNASMN1; SMN2NPC1TSHRKMT2A | |
| SCHEMBL4522298 | 0.79 | SIGMAR1 (0.56) | F2LMNATSHRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117024326-A | 5-amino substituted indole compound, preparation method thereof and application thereof in anti-acetylcholinesterase medicine | 平顶山学院 | 2023-11-10 | — | — | CN | disclosed |
| CN-111606824-B | Beta-amino nitrile compound and preparation method thereof | 东北师范大学 | 2023-03-14 | — | — | CN | disclosed |
| CN-111943912-A | Preparation method of 2-aminocinnamoyl alcohol ester derivative | 华侨大学 | 2020-11-17 | — | — | CN | disclosed |
| CN-111606824-A | Beta-amino nitrile compound and preparation method thereof | 东北师范大学 | 2020-09-01 | — | — | CN | disclosed |