Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | LCK | P06239 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28652107 | 0.85 | KDM4E (0.36) | HSD17B10ATMAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL935778 | 0.83 | HSD17B10 (0.49) | HSD17B10ATMAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL5250267 | 0.80 | TSHR (0.48) | HSD17B10L3MBTL1KMT2AGAAMAPT | |
| SCHEMBL28532275 | 0.76 | KDR (0.39) | HSD17B10AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL2226763 | 0.76 | AKR1C3 (0.61) | HSD17B10AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL16588574 | 0.73 | PTPN2 (0.54) | CYP1A2CYP2C19MAPTALDH1A1HPGD | |
| SCHEMBL12499964 | 0.69 | KDM4E (0.47) | HSD17B10ATMMEN1KMT2AGAA | |
| SCHEMBL20503830 | 0.69 | GAA (0.46) | HSD17B10ATMMEN1KMT2AGAA | |
| SCHEMBL29920315 | 0.69 | KDM4E (0.47) | HSD17B10ATMMEN1KMT2AGAA | |
| SCHEMBL7576787 | 0.69 | PTGER4 (0.39) | HSD17B10ATMCYP1A2GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117304046-A | Method for synthesizing 3, 5-dibromo-2-aminobenzaldehyde | 浙江浙邦制药有限公司 | 2023-12-29 | — | — | CN | claimed |
| CN-117304046-A | Method for synthesizing 3, 5-dibromo-2-aminobenzaldehyde | 浙江浙邦制药有限公司 | 2023-12-29 | — | — | CN | disclosed |
| CN-115963209-A | Method for detecting related substances in bromhexine hydrochloride injection | 海南葫芦娃药业集团股份有限公司 | 2023-04-14 | — | — | CN | disclosed |
| CN-109535010-B | Preparation method of bromhexine hydrochloride | 广州一品红制药有限公司 | 2021-10-26 | — | — | CN | disclosed |
| CN-112266329-A | Efficient production method of bromhexine hydrochloride | 江西亿友药业有限公司 | 2021-01-26 | — | — | CN | disclosed |