Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 20/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29692589 | 0.90 | STING1 (0.79) | STING1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL28507566 | 0.90 | STING1 (0.79) | STING1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL28512134 | 0.85 | STING1 (0.81) | STING1 | |
| SCHEMBL28905709 | 0.83 | STING1 (0.56) | STING1 | |
| SCHEMBL22857879 | 0.83 | STING1 (0.70) | STING1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL19437497 | 0.82 | STING1 (0.68) | STING1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL22135028 | 0.79 | STING1 (0.64) | STING1CYP3A4 | |
| SCHEMBL28510957 | 0.79 | STING1 (0.83) | STING1 | |
| SCHEMBL22857818 | 0.77 | STING1 (0.61) | STING1CYP3A4 | |
| SCHEMBL19449078 | 0.76 | STING1 (1.00) | STING1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112279835-B | Aromatic ring or aromatic heterocyclic imidazole compound, preparation method and pharmaceutical application thereof | 中国医学科学院药物研究所 | 2022-07-22 | — | — | CN | disclosed |
| CN-112279835-A | Aromatic ring or aromatic heterocyclic imidazole compound, preparation method and pharmaceutical application thereof | 中国医学科学院药物研究所 | 2021-01-29 | — | — | CN | disclosed |