SCHEMBL28508157

SCHEMBL28508157

C=CCNCCOPOCC

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.34
ADRB1 P08588 1/20 0.34
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
POLB P06746 1/20 0.31
HTT P42858 1/20 0.31
CNR1 P21554 1/20 0.30
CNR2 P34972 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21834711 0.81 ADRB2 (0.34) ADRB2ADRB1HTT
SCHEMBL20535312 0.75
SCHEMBL23900908 0.72 CYP1A2 (0.42) ADRB2ADRB1KDM4EALDH1A1SMN1; SMN2
SCHEMBL5142254 0.70
SCHEMBL13295739 0.68
SCHEMBL14097735 0.67 MEN1 (0.42) POLB
SCHEMBL468002 0.67
SCHEMBL368094 0.65 ADRB2 (0.35) ADRB2ADRB1ALDH1A1SMN1; SMN2HTT
SCHEMBL29557311 0.65 KMT2A (0.33)
SCHEMBL377600 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12517282-B2 Contact lenses containing light absorbing regions and methods for their preparation JOHNSON & JOHNSON VISION CARE, INC. (US) 2026-01-06 US disclosed
CN-115698190-B Light stability simulation of macular pigment 强生视力健公司 2025-06-17 CN disclosed
CN-114096514-B Polymerizable amino acid-based compounds and ophthalmic devices made therefrom 强生视力健公司 2025-06-17 CN disclosed
CN-112437889-B Silicone hydrogel contact lenses with non-uniform morphology 强生视力健公司 2025-06-17 CN disclosed
CN-114144248-B Imidazolium zwitterionic polymerizable compounds and ophthalmic devices incorporating same 强生视力健公司 2025-06-03 CN disclosed
CN-119365797-A Ophthalmic devices comprising light stable mimics of macular pigments and other visible light filters 强生视力健公司 2025-01-24 CN disclosed
CN-113874781-B Contact lens comprising photosensitive chromophore and package therefor 强生视力健公司 2024-12-31 CN disclosed
CN-119173379-A Ophthalmic lens and its manufacture by in-mold modification 强生视力健公司 2024-12-20 CN disclosed
CN-112449635-B Polymerizable fused tricyclic compounds as UV and visible light absorbers 强生视力健公司 2024-10-29 CN disclosed
US-11993037-B1 Contact lens displaying improved vision attributes JOHNSON & JOHNSON VISION CARE, INC. (US) 2024-05-28 US disclosed
CN-113939762-B Contact lenses exhibiting improved visual properties 强生视力健公司 2024-04-12 CN disclosed
CN-112334444-B Polymerizable absorbers for UV and high energy visible light 强生视力健公司 2023-11-21 CN disclosed
CN-112218923-B Polymerizable absorbers for UV and high energy visible light 强生视力健公司 2023-08-04 CN disclosed
CN-116355127-A Polymerizable absorbers for UV and high energy visible light 强生视力健公司 2023-06-30 CN disclosed
CN-115698190-A Photostable simulation of macular pigment 强生视力健公司 2023-02-03 CN disclosed
CN-109563293-B Polymer compositions containing grafted polymer networks and methods for making and using the same 庄臣及庄臣视力保护公司 2022-06-03 CN disclosed
CN-109415474-B Silicone hydrogels comprising high levels of polyamides 庄臣及庄臣视力保护公司 2022-05-10 CN disclosed
CN-113874781-A Contact lenses containing photosensitive chromophores and packaging therefor 强生视力健公司 2021-12-31 CN disclosed
CN-109790353-B Silicone hydrogels comprising polyamides 庄臣及庄臣视力保护公司 2021-12-03 CN disclosed
CN-112218923-A Polymerizable absorbers for UV and high energy visible light 强生视力健公司 2021-01-12 CN disclosed