SCHEMBL28508307

SCHEMBL28508307

C=C(C)C(=O)O[C@H]1CC[C@@H](C(C)(C)C)CC1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.46
APOBEC3A P31941 1/20 0.45
APOBEC3G Q9HC16 1/20 0.45
SMN1; SMN2 Q16637 3/20 0.44
HTT P42858 3/20 0.44
KDM4E B2RXH2 1/20 0.44
CYP19A1 P11511 1/20 0.43
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
GAA P10253 1/20 0.40
EPHX1 P07099 1/20 0.36
ALDH1A1 P00352 3/20 0.35
EPHX2 P34913 1/20 0.35
LIPA P38571 1/20 0.34
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
GLA P06280 1/20 0.32
HSD11B1 P28845 1/20 0.32
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22799034 1.00 MAPT (0.46) MAPTAPOBEC3AAPOBEC3GSMN1; SMN2HTT
SCHEMBL439526 1.00 MAPT (0.46) MAPTAPOBEC3AAPOBEC3GSMN1; SMN2HTT
SCHEMBL1291811 0.89 MAPT (0.36) MAPTAPOBEC3AAPOBEC3GSMN1; SMN2HTT
SCHEMBL18253569 0.87 MAPT (0.36) MAPTAPOBEC3AAPOBEC3GSMN1; SMN2HTT
SCHEMBL342182 0.86 ALDH1A1 (0.46) EPHX1ALDH1A1KMT2ATHRB
SCHEMBL25278 0.86
SCHEMBL372980 0.86 ALDH1A1 (0.46) EPHX1ALDH1A1KMT2ATHRB
SCHEMBL19982381 0.86 MAPT (0.35) MAPTAPOBEC3AAPOBEC3GSMN1; SMN2HTT
SCHEMBL10549632 0.84 SMN1; SMN2 (0.40) MAPTAPOBEC3AAPOBEC3GSMN1; SMN2HTT
SCHEMBL25175298 0.84 MAPT (0.45) MAPTAPOBEC3AAPOBEC3GSMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112118802-B Orthodontic articles prepared using polycarbonate diols and methods of making the same 3M创新有限公司 2021-12-07 CN claimed
CN-112118802-A Orthodontic articles prepared using polycarbonate diols and methods of making the same 3M创新有限公司 2020-12-22 CN claimed
CN-118414365-B Photocurable composition 斯特拉塔西斯公司 2025-05-16 CN disclosed
CN-118414365-A Photocurable composition 斯特拉塔西斯公司 2024-07-30 CN disclosed
CN-116982223-A Method for producing electromagnetic radiation-modifying articles, articles produced by these methods, apparatus, and method for modifying electromagnetic radiation 3M创新有限公司 2023-10-31 CN disclosed
WO-2022254270-A1 CURABLE LIQUID/LIQUID/SOLID MULTIPHASIC SUSPENSIONS 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-12-08 WO disclosed
CN-112118802-B Orthodontic articles prepared using polycarbonate diols and methods of making the same 3M创新有限公司 2021-12-07 CN disclosed
CN-113286560-A Orthodontic articles and methods of making and post-treating the same 3M创新有限公司 2021-08-20 CN disclosed
CN-112384188-A Orthodontic articles made using polycarbonate diols, polymerizable compositions, and methods of making articles 3M创新有限公司 2021-02-19 CN disclosed
CN-112118802-A Orthodontic articles prepared using polycarbonate diols and methods of making the same 3M创新有限公司 2020-12-22 CN disclosed
CN-112105332-A Photopolymerizable compositions, articles, and methods comprising urethane methacrylate polymers prepared using polycarbonate diols 3M创新有限公司 2020-12-18 CN disclosed