Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 8/20 | 0.38 |
| ▸ | FNTB | P49356 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28508309 | 1.00 | FNTA (0.38) | FNTAFNTBKDM4EATMPGGT1B | |
| SCHEMBL4836292 | 0.84 | HSD17B10 (0.39) | FNTAFNTBALDH1A1 | |
| SCHEMBL22692078 | 0.83 | PDK1 (0.33) | — | |
| SCHEMBL22692079 | 0.83 | PDK1 (0.33) | — | |
| SCHEMBL3493185 | 0.82 | CA1 (0.32) | FNTAFNTBKDM4EALDH1A1 | |
| SCHEMBL4294643 | 0.80 | KDM4E (0.43) | KDM4EALDH1A1 | |
| SCHEMBL4286026 | 0.80 | HPGD (0.49) | KDM4EALDH1A1 | |
| SCHEMBL3494104 | 0.80 | CA1 (0.35) | — | |
| SCHEMBL4788402 | 0.80 | CA1 (0.35) | — | |
| SCHEMBL16637819 | 0.80 | CA1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111989321-A | KRAS G12C inhibitors | 米拉蒂治疗股份有限公司 | 2020-11-24 | — | — | CN | disclosed |