Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 19/20 | 0.41 |
| ▸ | F11 | P03951 | 11/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 7/20 | 0.39 |
| ▸ | TPSB2 | P20231 | 5/20 | 0.38 |
| ▸ | PLG | P00747 | 2/20 | 0.38 |
| ▸ | PLAU | P00749 | 2/20 | 0.38 |
| ▸ | F7 | P08709 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F9 | P00740 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21439011 | 0.92 | CFD (0.40) | CFDF11KLKB1TPSB2PLG | |
| SCHEMBL21439012 | 0.92 | CFD (0.40) | CFDF11KLKB1TPSB2PLG | |
| SCHEMBL28943915 | 0.90 | CFD (0.36) | CFDF11KLKB1 | |
| SCHEMBL21545083 | 0.84 | CFD (0.41) | CFDF11KLKB1TPSB2PLG | |
| SCHEMBL28506712 | 0.84 | CFD (0.41) | CFDF11KLKB1TPSB2PLG | |
| SCHEMBL21545082 | 0.84 | CFD (0.41) | CFDF11KLKB1TPSB2PLG | |
| SCHEMBL28504086 | 0.84 | CFD (0.55) | CFDF11KLKB1TPSB2PLG | |
| SCHEMBL28504080 | 0.82 | CFD (0.43) | CFDF11KLKB1TPSB2PLG | |
| SCHEMBL28504124 | 0.78 | CFD (0.51) | CFDF11KLKB1TPSB2PLG | |
| SCHEMBL28515590 | 0.77 | CFD (0.49) | CFDF11KLKB1TPSB2PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555570-A | Oral complement factor D inhibitors | 拜奥克里斯特制药公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-112272553-A | Substituted benzofurans, benzopyrrole, benzothiophenes and structurally related complement inhibitors | 拜奥克里斯特制药公司 | 2021-01-26 | — | — | CN | disclosed |