Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.73 |
| ▸ | PNLIP | P16233 | 5/20 | 0.70 |
| ▸ | PGR | P06401 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | TGM2 | P21980 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benodanil SCHEMBL29402073 | 0.85 | MEN1 (1.00) | MEN1KMT2ATDP1LMNAHPGD | |
| Benodanil SCHEMBL18736 | 0.85 | MEN1 (1.00) | MEN1KMT2ATDP1LMNAHPGD | |
| SCHEMBL19747244 | 0.84 | NPC1 (0.70) | MEN1KMT2ATDP1PNLIPMAPK1 | |
| SCHEMBL12189610 | 0.84 | MEN1 (0.78) | MEN1KMT2APNLIPPGRL3MBTL1 | |
| SCHEMBL13927137 | 0.82 | MEN1 (0.81) | MEN1KMT2APNLIPPGRL3MBTL1 | |
| SCHEMBL13927136 | 0.82 | MEN1 (0.81) | MEN1KMT2APNLIPPGRL3MBTL1 | |
| SCHEMBL28688539 | 0.82 | MEN1 (0.64) | MEN1KMT2ATDP1PNLIPLMNA | |
| SCHEMBL20022688 | 0.81 | PNLIP (0.70) | MEN1KMT2ATDP1PNLIPPGR | |
| SCHEMBL5674964 | 0.81 | PNLIP (0.70) | MEN1KMT2APNLIPPGRL3MBTL1 | |
| SCHEMBL29168845 | 0.81 | TDP1 (0.62) | MEN1KMT2ATDP1L3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112110877-B | Benzisoselenazolone derivative, preparation method and application thereof in anti-coronavirus medicament | 青岛大学 | 2023-09-08 | — | — | CN | disclosed |
| CN-112110877-A | Benzisoselenazolone derivative, preparation method and application in anti-coronavirus drugs | 青岛大学 | 2020-12-22 | — | — | CN | disclosed |