Acetic Acid

Acetic Acid

SCHEMBL28510404

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nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NOS3 known ✓ P29474 1/20 0.32
NOS1 known ✓ P29475 1/20 0.32
NOS2 known ✓ P35228 1/20 0.32
ALOX15 P16050 1/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
GAA P10253 1/20 0.32
CYP1A2 P05177 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ALDH1A1 P00352 1/20 0.31
OTC P00480 1/20 0.31
NOD1 Q9Y239 2/20 0.30
DPP7 Q9UHL4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1419586 0.97 ALOX15 (0.34) ALOX15MEN1KMT2AGAANOS3
SCHEMBL3732825 0.97 ALOX15 (0.34) ALOX15MEN1KMT2AGAANOS3
SCHEMBL1881323 0.97 ALOX15 (0.34) ALOX15MEN1KMT2AGAANOS3
Hydrochloric Acid SCHEMBL28067883 0.95 ALOX15 (0.33) ALOX15MEN1KMT2AGAANOS3
Hydrochloric Acid SCHEMBL28067882 0.95 ALOX15 (0.33) ALOX15MEN1KMT2AGAANOS3
SCHEMBL1697162 0.93 ALOX15 (0.36) ALOX15MEN1KMT2ANOS3NOS1
SCHEMBL27763046 0.93 ALOX15 (0.36) ALOX15MEN1KMT2ANOS3NOS1
SCHEMBL3722670 0.93 ALOX15 (0.36) ALOX15MEN1KMT2ANOS3NOS1
Hydrochloric Acid SCHEMBL9762986 0.91 ALOX15 (0.36) ALOX15MEN1KMT2ANOS3NOS1
SCHEMBL8015555 0.89 ALOX15 (0.31) ALOX15MEN1KMT2AGAANOS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112220938-A Magnetic resonance imaging contrast agent based on metal fullerene and preparation method thereof 宜春学院 2021-01-15 CN disclosed