Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | FEN1 | P39748 | 4/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31114170 | 1.00 | CYP11B1 (0.43) | CYP11B1CYP11B2ALDH1A1SMN1; SMN2KIF11 | |
| SCHEMBL5835011 | 0.85 | KMT2A (0.41) | ALDH1A1SMN1; SMN2KIF11KDM1ACYP1A2 | |
| SCHEMBL13765803 | 0.83 | S1PR1 (0.48) | CYP11B1CYP11B2ALDH1A1SMN1; SMN2IDO1 | |
| SCHEMBL6301359 | 0.81 | NPSR1 (0.42) | ALDH1A1KIF11IDO1KDM1AKMT2A | |
| SCHEMBL1416833 | 0.81 | NPC1 (0.50) | CYP11B1CYP11B2IDO1KDM1ANPSR1 | |
| SCHEMBL7088718 | 0.80 | KDM1A (0.46) | ALDH1A1SMN1; SMN2KIF11KDM1AKMT2A | |
| SCHEMBL31114090 | 0.79 | CASP3 (0.44) | ALDH1A1KIF11IDO1KMT2ANPSR1 | |
| SCHEMBL16915425 | 0.79 | HSD17B10 (0.48) | ALDH1A1KIF11IDO1KDM1ACYP1A2 | |
| Hydrochloric Acid SCHEMBL7092694 | 0.79 | KDM1A (0.45) | ALDH1A1SMN1; SMN2KIF11KDM1AKMT2A | |
| Hydrochloric Acid SCHEMBL7085695 | 0.79 | KDM1A (0.45) | ALDH1A1SMN1; SMN2KIF11KDM1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112898196-A | Potent soluble epoxide hydrolase inhibitors | 艾科西斯有限责任公司 | 2021-06-04 | — | — | CN | disclosed |
| CN-106163521-B | Potent soluble epoxide hydrolase inhibitors | 艾科西斯有限责任公司 | 2021-02-09 | — | — | CN | disclosed |