Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1813491 | 0.81 | ALDH1A1 (0.41) | ALDH1A1TSHRPTGS1HSD17B10TDP1 | |
| SCHEMBL1290659 | 0.79 | ALDH1A1 (0.44) | ALDH1A1TSHRPTGS1HSD17B10TDP1 | |
| SCHEMBL35205 | 0.79 | ALDH1A1 (0.56) | ALDH1A1TSHRPTGS1HSD17B10TDP1 | |
| SCHEMBL10300839 | 0.77 | SOAT1 (0.42) | ALDH1A1TSHRPTGS1 | |
| SCHEMBL10776617 | 0.76 | ALDH1A1 (0.53) | ALDH1A1TSHRPTGS1HSD17B10TDP1 | |
| SCHEMBL9861711 | 0.76 | ALDH1A1 (0.53) | ALDH1A1TSHRPTGS1HSD17B10TDP1 | |
| SCHEMBL11866461 | 0.76 | ALDH1A1 (0.36) | ALDH1A1TSHRPTGS1HSD17B10TDP1 | |
| SCHEMBL8986098 | 0.76 | PTGS1 (0.36) | ALDH1A1TSHRPTGS1HSD17B10TDP1 | |
| SCHEMBL29210332 | 0.76 | ALDH1A1 (0.44) | ALDH1A1TSHRPTGS1HSD17B10ALOX15 | |
| SCHEMBL5433574 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112300235-B | Benzimidazole derivative BI321 and preparation method and application thereof | 中国人民解放军东部战区总医院 | 2021-12-21 | — | — | CN | claimed |
| CN-112920241-B | Benzimidazole derivative BI308 and preparation method and application thereof | 中国人民解放军东部战区总医院 | 2021-12-21 | — | — | CN | claimed |
| CN-112812145-B | Benzimidazole derivative BI293 and preparation method and application thereof | 中国人民解放军东部战区总医院 | 2021-12-21 | — | — | CN | claimed |
| CN-112375112-B | Benzimidazole derivative BI361 and preparation method and application thereof | 中国人民解放军东部战区总医院 | 2021-12-21 | — | — | CN | claimed |
| CN-112812145-A | Benzimidazole derivative BI293 and preparation method and application thereof | 中国人民解放军东部战区总医院 | 2021-05-18 | — | — | CN | claimed |
| CN-112375112-A | Benzimidazole derivative BI361 and preparation method and application thereof | 中国人民解放军东部战区总医院 | 2021-02-19 | — | — | CN | claimed |
| CN-112300235-A | Benzimidazole derivative BI321 and preparation method and application thereof | 中国人民解放军东部战区总医院 | 2021-02-02 | — | — | CN | claimed |
| CN-112300235-B | Benzimidazole derivative BI321 and preparation method and application thereof | 中国人民解放军东部战区总医院 | 2021-12-21 | — | — | CN | disclosed |
| CN-112920241-B | Benzimidazole derivative BI308 and preparation method and application thereof | 中国人民解放军东部战区总医院 | 2021-12-21 | — | — | CN | disclosed |
| CN-112375112-B | Benzimidazole derivative BI361 and preparation method and application thereof | 中国人民解放军东部战区总医院 | 2021-12-21 | — | — | CN | disclosed |
| CN-112812145-B | Benzimidazole derivative BI293 and preparation method and application thereof | 中国人民解放军东部战区总医院 | 2021-12-21 | — | — | CN | disclosed |
| CN-112920241-A | Benzimidazole derivative BI308 and preparation method and application thereof | 中国人民解放军东部战区总医院 | 2021-06-08 | — | — | CN | disclosed |
| CN-112812145-A | Benzimidazole derivative BI293 and preparation method and application thereof | 中国人民解放军东部战区总医院 | 2021-05-18 | — | — | CN | disclosed |
| CN-112375112-A | Benzimidazole derivative BI361 and preparation method and application thereof | 中国人民解放军东部战区总医院 | 2021-02-19 | — | — | CN | disclosed |
| CN-112300235-A | Benzimidazole derivative BI321 and preparation method and application thereof | 中国人民解放军东部战区总医院 | 2021-02-02 | — | — | CN | disclosed |