Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 10/20 | 0.81 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenoxazine SCHEMBL28032695 | 0.93 | ALOX5 (0.94) | ALOX5MEN1KMT2AGAANPSR1 | |
| Phenoxazine SCHEMBL28844098 | 0.90 | ALOX5 (1.00) | ALOX5MEN1KMT2AGAANPSR1 | |
| Phenoxazine SCHEMBL29355714 | 0.90 | ALOX5 (1.00) | ALOX5MEN1KMT2AGAANPSR1 | |
| Phenoxazine SCHEMBL7862 | 0.90 | ALOX5 (1.00) | ALOX5MEN1KMT2AGAANPSR1 | |
| Phenoxazine SCHEMBL6310178 | 0.90 | ALOX5 (1.00) | ALOX5MEN1KMT2AGAANPSR1 | |
| SCHEMBL24633134 | 0.88 | ALOX5 (0.63) | ALOX5MEN1KMT2AGAAMAPT | |
| SCHEMBL22902405 | 0.88 | ALOX5 (0.63) | ALOX5MEN1KMT2AGAAMAPT | |
| Phenoxazine SCHEMBL5808288 | 0.87 | ALOX5 (0.94) | ALOX5MEN1KMT2AGAANPSR1 | |
| Phenoxazine SCHEMBL20840431 | 0.87 | ALOX5 (0.94) | ALOX5MEN1KMT2AGAANPSR1 | |
| Phenoxazine SCHEMBL25275195 | 0.87 | ALOX5 (0.94) | ALOX5MEN1KMT2AGAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114957085-A | Synthetic method and application of polycyano-substituted indole heterocyclic compound | 华南师范大学 | 2022-08-30 | — | — | CN | claimed |
| CN-114957085-B | Synthetic method and application of polycyano substituted indole heterocyclic compound | 华南师范大学 | 2023-11-14 | — | — | CN | disclosed |
| CN-114957085-A | Synthetic method and application of polycyano-substituted indole heterocyclic compound | 华南师范大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-108516970-B | Heterocyclic bridged phenyl ethylene derivatives, and preparation method and application thereof | 华南理工大学 | 2021-01-19 | — | — | CN | disclosed |