Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 6/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ACACA | Q13085 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6055121 | 0.82 | NQO1 (0.58) | NQO1MEN1KMT2ATAAR1ACACB | |
| SCHEMBL11251522 | 0.81 | AOC3 (0.58) | MEN1KMT2AL3MBTL1RAB9ATDP1 | |
| SCHEMBL6055189 | 0.80 | NQO1 (0.61) | NQO1MEN1KMT2AACACBL3MBTL1 | |
| SCHEMBL18905326 | 0.80 | MEN1 (0.38) | MEN1KMT2AL3MBTL1HPGDTDP1 | |
| SCHEMBL6055165 | 0.79 | MEN1 (0.59) | NQO1MEN1KMT2ATAAR1ACACB | |
| SCHEMBL8130343 | 0.79 | NQO1 (0.54) | NQO1MEN1KMT2ATAAR1ACACB | |
| SCHEMBL7148796 | 0.79 | NQO1 (0.54) | NQO1MEN1KMT2ATAAR1L3MBTL1 | |
| SCHEMBL11603750 | 0.78 | NQO1 (0.64) | NQO1MEN1KMT2AACACBL3MBTL1 | |
| SCHEMBL13558759 | 0.78 | NQO1 (0.64) | NQO1MEN1KMT2AACACBL3MBTL1 | |
| SCHEMBL9114461 | 0.78 | NQO1 (0.64) | NQO1MEN1KMT2AACACBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112321440-B | Amino phenyl ketone compound and preparation method and application thereof | 南方医科大学 | 2021-09-24 | — | — | CN | disclosed |
| CN-112321440-A | Amino phenyl ketone compound and preparation method and application thereof | 南方医科大学 | 2021-02-05 | — | — | CN | disclosed |