Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.57 |
| ▸ | RXRA | P19793 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.52 |
| ▸ | MITF | O75030 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.52 |
| ▸ | RRM1 | P23921 | 3/20 | 0.50 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28510880 | 1.00 | ERN1 (0.57) | ERN1RXRAMAPTHPGDLMNA | |
| SCHEMBL21831542 | 0.81 | RXRA (0.57) | ERN1RXRAMAPTHPGDLMNA | |
| SCHEMBL21831540 | 0.81 | RXRA (0.57) | ERN1RXRAMAPTHPGDLMNA | |
| SCHEMBL7915280 | 0.80 | ERN1 (0.70) | ERN1MAPTHPGDNPC1HTT | |
| SCHEMBL7915285 | 0.80 | ERN1 (0.70) | ERN1MAPTHPGDNPC1HTT | |
| SCHEMBL20338596 | 0.80 | RXRA (0.59) | RXRAMAPTHPGDLMNANPSR1 | |
| SCHEMBL4428406 | 0.80 | RXRA (0.59) | RXRAMAPTHPGDLMNANPSR1 | |
| SCHEMBL8709084 | 0.77 | MAPT (0.66) | RXRAMAPTHPGDLMNANPSR1 | |
| SCHEMBL31618276 | 0.77 | MAPT (0.66) | RXRAMAPTHPGDLMNANPSR1 | |
| SCHEMBL8709081 | 0.77 | MAPT (0.66) | RXRAMAPTHPGDLMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110041340-B | 6-aryl-benzofuran carbazole compounds and preparation and application thereof | 浙江大学 | 2020-12-18 | — | — | CN | disclosed |