Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4224923 | 0.83 | CNR1 (0.52) | CNR1 | |
| SCHEMBL2637480 | 0.82 | SMN1; SMN2 (0.48) | CNR1MAPTKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL14013151 | 0.80 | SLC6A4 (0.40) | CNR1KDM4ESLC6A4DRD2DRD4 | |
| SCHEMBL28517116 | 0.80 | SLC6A4 (0.55) | SLC6A4DRD2DRD4CCNB2CDK1 | |
| SCHEMBL27773025 | 0.78 | KMT2A (0.41) | MAPTLMNAKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL27842059 | 0.78 | CNR1 (0.43) | CNR1MAPTLMNAKMT2AHTT | |
| SCHEMBL6869073 | 0.77 | CNR1 (0.42) | CNR1MAPTLMNAKMT2AHTT | |
| SCHEMBL4433323 | 0.77 | MAPT (0.52) | CNR1MAPTLMNAKMT2AHTT | |
| SCHEMBL15556551 | 0.75 | CNR1 (0.63) | CNR1MAPTLMNAKMT2AHTT | |
| SCHEMBL6359772 | 0.75 | NAMPT (0.42) | SLC6A4QDPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112243439-A | Pyrrolo [2,3-B ] pyridines or pyrrolo [2,3-B ] pyrazines as HPK1 inhibitors and uses thereof | 百济神州有限公司 | 2021-01-19 | — | — | CN | disclosed |