Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | PARP1 | P09874 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.50 |
| ▸ | VCP | P55072 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.47 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28511011 | 1.00 | MAPT (0.55) | MAPTTP53LMNAPARP1MEN1 | |
| SCHEMBL21484826 | 0.90 | CSNK2A1 (0.55) | MAPTLMNAPARP1MEN1KMT2A | |
| SCHEMBL21484829 | 0.90 | CSNK2A1 (0.55) | MAPTLMNAPARP1MEN1KMT2A | |
| SCHEMBL28511750 | 0.89 | KDM4E (0.52) | MAPTTP53LMNAPARP1MEN1 | |
| SCHEMBL21484629 | 0.89 | EGFR (0.62) | MAPTTP53LMNAMEN1KMT2A | |
| SCHEMBL28511749 | 0.89 | KDM4E (0.52) | MAPTTP53LMNAPARP1MEN1 | |
| SCHEMBL21484718 | 0.88 | KMT2A (0.59) | MAPTLMNAMEN1KMT2AADORA3 | |
| SCHEMBL21495011 | 0.87 | MAPT (0.59) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL21484838 | 0.87 | MAPT (0.59) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL21484912 | 0.87 | MEN1 (0.52) | MAPTTP53LMNAPARP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112313229-A | Substituted aminothiazoles as inhibitors of nucleases | 马萨里克大学 | 2021-02-02 | — | — | CN | disclosed |