SCHEMBL28511682

SCHEMBL28511682

[CH2]CC(c1ccccc1)C(C)C(C)C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 4/20 0.52
AOC3 Q16853 2/20 0.39
SLC6A2 P23975 4/20 0.39
SLC6A4 P31645 4/20 0.39
SLC6A3 Q01959 4/20 0.39
PKM P14618 2/20 0.38
HTR2A P28223 2/20 0.36
CHRM2 P08172 1/20 0.36
ADRA1A P35348 1/20 0.36
RGS12 O14924 1/20 0.36
GLA P06280 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
ALOX15 P16050 1/20 0.36
TSHR P16473 1/20 0.36
ALOX12 P18054 1/20 0.36
ADRA2C P18825 1/20 0.36
NFKB1 P19838 1/20 0.36
CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6325160 0.86 TAAR1 (0.61) TAAR1AOC3SLC6A2SLC6A4SLC6A3
SCHEMBL3624306 0.80 TAAR1 (0.48) TAAR1AOC3SLC6A2SLC6A4SLC6A3
SCHEMBL28411588 0.77 TAAR1 (0.45) TAAR1AOC3CHRM2ADRA1AHSD17B10
SCHEMBL11478651 0.76 HKDC1 (0.55) TAAR1AOC3SLC6A2SLC6A4SLC6A3
SCHEMBL4820239 0.75 TAAR1 (0.41) TAAR1SLC6A2SLC6A4SLC6A3HTR2A
SCHEMBL184799 0.72 TAAR1 (0.58) TAAR1AOC3ADRA2CLMNATRPA1
SCHEMBL6704370 0.72 TAAR1 (0.58) TAAR1AOC3ADRA2CLMNATRPA1
SCHEMBL27470172 0.72 TAAR1 (0.58) TAAR1AOC3ADRA2CLMNATRPA1
SCHEMBL11529211 0.71 DPP4 (0.56) TAAR1AOC3SLC6A2SLC6A4SLC6A3
Hydrochloric Acid SCHEMBL10398962 0.70 TAAR1 (0.56) TAAR1AOC3ADRA2CLMNATRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112154147-A Substituted phenylthiouracils, their salts and their use as herbicides 先正达农作物保护股份公司 2020-12-29 CN disclosed