Pyrazole

Pyrazole

SCHEMBL28511802

c1ccc2c[nH]cc2c1.c1cn[nH]c1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.31
IDO1 P14902 1/20 0.31
CDK2 P24941 1/20 0.31
AKT1 P31749 1/20 0.30
AKT2 P31751 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridazine SCHEMBL3665889 0.88
Naphthalene SCHEMBL338595 0.86 CYP2A6 (0.42) HSP90AA1IDO1CDK2
Anthracene SCHEMBL27373164 0.82 ALDH1A1 (0.39) HSP90AA1IDO1CDK2
Anthracene SCHEMBL28769412 0.79 ALDH1A1 (0.33)
Phthalazine SCHEMBL28105918 0.78 HSP90AA1 (0.35) HSP90AA1IDO1CDK2AKT1AKT2
Phenazine SCHEMBL28301634 0.77 MAPT (0.52)
Pyrazole SCHEMBL5664483 0.75
Pyrazole SCHEMBL30626480 0.75
SCHEMBL60689 0.75
Pyrazole SCHEMBL30854861 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112239472-B Organic compound, organic light emitting diode including the same, and organic light emitting device 乐金显示有限公司 2023-06-16 CN disclosed
CN-112239472-A Organic compound, organic light emitting diode including the same, and organic light emitting device 乐金显示有限公司 2021-01-19 CN disclosed